楊鲲,教授,博士生導師,解剖學教研室,郵箱:yangk@ujs.edu.cn。
【學習工作經曆】
1988-1994,中國人民解放軍第四軍醫大學,本科生,醫學學士,
1995-1997,第四軍醫大學,人體解剖與組織胚胎學碩士研究生,醫學碩士,
1998-2002,第四軍醫大學,人體解剖與組織胚胎學博士研究生,醫學博士,
2014-至今,det365娱乐官网入口解剖學教研室,特聘教授,教授。
【教改科研項目】
人體解剖學(痛與鎮痛的神經生物學機制),2016.07-2019.06;江蘇省教育廳江蘇特聘教授項目。
【代表性論文】
[1] Zhao M, Shao C, Dong J, Chen Q, Ma R, Jiang P, Zhang W-N, Yang K. GABAB receptors constrain glutamate presynaptic release and postsynaptic actions in substantia gelatinosa of rat spinal cord. Brain Structure and Function, 2022 (in the press).
[2] Shao C, Dong J, Zhao M, Liu S, Wang X, Yu Y, Fang L, Zhu Z, Chen Q, Xiao X, Zhang W-N, Yang K. Presynaptic GABAB receptors differentially modulate GABA release from cholecystokinin and parvalbumin interneurons onto CA1 pyramidal neurons: a cell type-specific labeling and activating study. Neuroscience Letters, 772 (2022): 136448.
[3] Zhang M-M, Feng Y-P, Qiu X-T, Chen T, Bai Y, Feng J-M, Wang J-D, Chen Y, Zhang M-Z, Duan H-K, Zhao M, Teng Y-H, Cao J, Zang W-D, Yang K, Li Y-Q. Neurotensin attenuates nociception by facilitating inhibitory synaptic transmission in the mouse spinal cord. Frontiers in Neural Circuits, 15 (2021): 775215.
[4] Yang D, Yang XJ, Shao C, Yang K. Isoflurane decreases substantia gelatinosa neuron excitability and synaptic transmission from periphery in the rat spinal dorsal horn. NeuroReport, 32 (2021): 77-81.
[5] Shao C, Chen P, Chen Q, Zhao M, Zhang W-N, Yang K. Mu opioid receptors inhibit GABA release from parvalbumin interneuron terminals onto CA1 pyramidal cells. Biochemical and Biophysical Research Communications, 522 (2020): 1059-1062.
[6] 邵采鳳, 趙明薇, 陳茜, 楊鲲. 大鼠脊髓背角II、III層神經元的高爾基染色特征. 解剖學雜志, 43 (2020): 291-294.
[7] Liu Y, Yang XJ, Xia H, Tang C-M, Yang K. GABA releases from parvalbumin-expressing and unspecific GABAergic neurons onto CA1 pyramidal cells are differentially modulated by presynaptic GABAB receptors in mouse hippocampus. Biochemical and Biophysical Research Communications, 520 (2019): 449-452.
[8] 邵采鳳, 張雯玮, 胡朝婷, 王冉超, 接玉, 趙昶昀, 陳茜, 楊鲲. GABAB受體激動劑巴氯芬對大鼠中腦導水管周圍灰質興奮性及抑制性突觸的作用.中國藥理學通報,34 (2018): 1511-1515.
[9] Chen Q, Shao C, Jiang P, Yang K. Differential sensitivity of presynaptic and postsynaptic GABAB receptors in rat periaqueductal gray. Neuroreport, 28 (2017): 1221-1224.
[10] Li G, Shao C, Chen Q, Wang Q, Yang K. Accumulated GABA activates presynaptic GABAB receptors and inhibits both excitatory and inhibitory synaptic transmission in rat midbrain periaqueductal gray. NeuroReport, 28 (2017): 250-256.
[11] Yang K. Regulation of excitability in tonic firing substantia gelatinosa neurons of the spinal cord by small-conductance Ca2+-activated K+ channels. Neuropharmacology, 105 (2016): 15-24.
[12] Yang K. Postnatal excitability development and innervation by functional transient receptor potential vanilloid 1 (TRPV1) terminals in neurons of the rat spinal sacral dorsal commissural nucleus: an electrophysiological study. Molecular Neurobiology, 53 (2016): 6033-6042.
[13] Li G, Liu Z-L, Zhang W-N, Yang K. Blockade of presynaptic 4-aminopyridine-sensitive potassium channels increases initial neurotransmitter release probability, reinstates synaptic transmission altered by GABAB receptor activation in rat midbrain periaqueductal gray. NeuroReport, 27 (2016): 50-55.
[14] Yang K, Ma R, Wang Q, Jiang P, Li Y-Q. Optoactivation of parvalbumin neurons in the spinal dorsal horn evokes GABA release that is regulated by presynaptic GABAB receptors. Neuroscience Letters, 594 (2015): 55-59.
【教材與專著】
《人體解剖學理論與實驗學習指導》(第三版),2019年,北京:科學出版社。
【獲獎與專利】
中華醫學獎(一等獎,排名2/8)(中華醫學會;2004),
全國優秀博士論文(中華人民共和國教育部;2005),
全軍優秀博士學位論文(中國人民解放軍總參謀部;2005)。
【榮譽與兼職】
江蘇省解剖學會副理事長(2017- )。